Dry Eye Disease (DED) is one of the most common eye conditions that patients seek care for and cannot be disregarded as a trivial condition. Although the pathogenesis of dry eye disease is not fully understood, it is recognized that inflammation has a prominent role in the development and propagation of this debilitating condition. (2,3,4,5,6).
Benefits of Omega-3 in Dry Eye Symptom
When there is an imbalance in the ratio of healthy fats, of omega-3s and omega-6s, the meibomian glands may become inflamed due to the change in composition of the meibum and the oil becomes viscous.8 The thickening can result in a blocking of the Meibomian Glands and potentially impact the production of the important tear lipid layer.
– Without the lipid layer, the aqueous layer evaporates, causing the ocular surface to become irritated.
– To improve occasional dry eye symptoms, the Meibomian Gland’s oil must be normalized.
Introducing PRN Dry Eye Omega-Benefits®
– PRN Dry Eye Omega-Benefits® are produced in a highly absorbable form (7)
– Clinical study shows that PRN Dry Eye Omega-Benefits® improves tears osmolarity in 6 weeks (8)
1.Epitropoulos A., et al., Cornea. 2016 Sep; 35(9): 1185–1191. Published online 2016 Jul 20. doi: 10.1097/ICO.0000000000000940
2.Pflugfelder SC, de Paiva CS, Li DQ, Stern ME. Epithelial-immune cell interaction in dry eye. Cornea 2008 Sep; 27 Suppl 1:S9-11
3.Enríquez-de-Salamanca A, Calder V, Gao J, et al. Cytokine responses by conjunctival epithelial cells: an in vitro model of ocular inflammation. 2008 Oct;44(1):160-7.
4.Paiva CS, Pflugfelder SC. Rationale for anti-inflammatory therapy in dry eye syndrome. Arq Bras Oftalmol . 2008 Nov-Dec;71(6 Suppl):89-95. Review.
5.Lemp MA. Advances in understanding and managing dry eye disease. Am J Ophthalmol . 2008 Sep;146(3):350-356.
6.Stevenson W, Chauhan SK, Dana R. Dry eye disease: an immune-mediated ocular surface disorder. Arch Ophthalmol . 2012 Jan;130(1):90-100
7.Dyerberg J et al, Bioavailability of marine n-3 acid formulations, Prostaglandins Leukotrines Essent. Fatty Acids (2010), doi: 10.1016/j.plefa.2010.06.007.
8.Macsai, M. et al.The Role Of Omega-3 Dietary Supplementation in Blepharitis And Meibomian Gland Dysfunction (An Aos Thesis),Trans Am Ophthalmol Soc 2008;106:336-356.
Omega-3 in refractive surgery brochure